Stress factors such as handling, sudden environmental changes, heat, feed programmes and diet composition changes, vaccination, disease challenges, infections, impaired immune response are affecting animal health and productivity.
Animals possess limited natural resistance and immunity against such stresses leading often to oxidative stress where the animal is no longer capable of detoxifying the reactive oxygen species at cell level at the rate they are formed. The impact of such stress factors get worsened and amplified in the presence of toxins.
1. Preventing Oxidative stress: with selected protective antioxidants providing cellular support against the damaging effects of free radicals on the intestinal microbiota, tissues and cells. Dealing with oxidative stress requires more energy from the animal that could otherwise be used for growth, longevity, fertility and overall animal productivity.
2. Liver & Kidney support with selected plant extracts proven to support these organs function in case of toxic stressors (toxin blockade at membrane level, protein synthesis enhancement, antibiotic activity, anti-inflammatory effect...)
3. Reducing immune suppression & strengthening the animal’s natural immune response: with the use of selected plant extracts and specific, biological response modifiers. Chronic mycotoxin exposure increases susceptibility to infectious diseases weakening immune responses.
4. Biotransformation and binding of Fusarium producing toxins modifying such toxic molecules into less harmful or polar components that can be more easily excreted by the organism
5. Binding & Adsorption. Capturing of water soluble (polar) toxins and reducing their bioavailability. Both highly adsorbent mineral clays and yeast extracts rich in gluco-mannans are used to adsorb mycotoxins efficiently, selectively and rapidly thus, reducing their toxic bio-availability in the organism.
A new avenue to measure the impact of toxins on animals
Innovad has collaborated with the University of Ghent and is funding breakthrough research on novel ways to evaluate the systemic impact of feed toxins and their intermediates on animals. This new research focuses on exposure assessment, as it is identifying novel biomarkers and is developing the appropriate analytical tools to determine toxic metabolites in animal biofluids. Such Biomonitoring could provide us with more reliable data related to animal intoxication via contaminated feed and/or stress in situ Thus, it has great potential for significant economic impact in animal farming.